The Science Behind 2before Blackcurrant Berry Pre-Workout

The Science

Improves Athletic Performance
Cognitive Benefits
Improves Blood Flow
Supports Immunity
Improves Recovery After Exercise
Manages Inflammation for Tissue Repair
Supports Training Adaption

IMPROVES ATHLETIC PERFORMANCE

A number of clinical studies have demonstrated New Zealand blackcurrant can improve athletic performance. Many different mechanisms have been investigated including cardiovascular, anti-inflammatory, oxidative stress management, and metabolic improvements.

Citations

Braakhuis AJ, Hopkins WG, Lowe TE. Effects of dietary antioxidants on training and performance in female runners. Eur J Sport Sci. 2014;14(2):160-8.

www.doi.org/10.1080/17461391.2013.785597

COGNITIVE BENEFITS

A few clinical studies have shown that blackcurrant extract can improve human cognitive function and the inhibition of monoamine oxidase-B and increased monoamine neurotransmitters appears to play a role. Another study demonstrates that blackcurrant may improve self-motivation to adhere to an exercise regime (Lomiwes et al. 2019).

Citations

Watson AW, Haskell-Ramsay CF, O’Kennedy D, Cooney JM, Trower T, Scheepens A. Acute supplementation with blackcurrant extracts modulates cognitive functioning and inhibits monoamine oxidase-B in healthy young adults. J Func Food 2015 Aug:17:524-539

www.doi.org/10.1016/j.jff.2015.06.005

Watson AW, Scheepens A, Kennedy DO, Cooney JM, Trower TM, Haskell-Ramsay CF. The pharmacodynamic profile of "Blackadder" blackcurrant juice effects upon the monoamine axis in humans: A randomised controlled trial. Nutr Neurosci. 2018 Oct 5:1-10.

www.doi.org/10.1080/1028415X.2018.1525950

Lomiwes D, Ha B, Ngametua N, Burr NS, Cooney JM, Trower TM, Sawyer G, Hedderley D, Hurst RD, Hurst SM. Timed consumption of a New Zealand blackcurrant juice support positive affective responses during a self-motivated moderate walking exercise in healthy sedentary adults. Journal of the International Society of Sports Nutrition. 2019 Dec;16(1):1-4.

www.doi.org/10.1186/s12970-019-0300-0

IMPROVES BLOOD FLOW

Clinical evidence shows that blackcurrant extract can improve blood flow. It can lower systolic, diastolic, and mean arterial blood pressure; increase cardiac output and stroke volume; decrease total peripheral resistance; maintain forearm blood flow (Barnes et al. 2018; Matsumoto et al. 2005); and increase circulation in the cold (Takenami et al. 2004).

Citations

Takenami,E. Kurashige,K.I. Matsumoto, H. Honma,T. Osada, T. Okubo, M. Hamaoka,T. Improvement of cold water immersion induced circulation impairment by blackcurrant extract intake-the investigation on cold constitutional women. J Jap Soc Ther. 2004; 23:194–201.

Matsumoto H, Takenami E, Iwasaki-Kurashige K, Osada T, Katsumura T, Hamaoka T. Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans. Eur J Appl Physiol. 2005 May;94(1-2):36-45.

www.doi.org/10.1007/s00421-004-1279-y

Barnes M, Perry B, Hurst R, Lomiwes D. Effects of blackcurrant extract on peripheral blood flow and muscular endurance. Med Sci Sports Ex 2018 May:50(5S):720

www.doi.org/10.1249/01.mss.0000538374.17437.0b

SUPPORTS IMMUNITY

New Zealand blackcurrants have been shown to activate the body’s immune defenses. In one study, New Zealand blackcurrant increased circulating neutrophils, the expression of neutrophil surface receptors, and helped maintain the ability of the neutrophils to phagocytose infectious bacteria (Hurst et al. 2019). In another study, 5-weeks supplementation with blackcurrant extract increased levels of IL-10, which was correlated with enhanced antioxidant status (Hurst et al. 2020).

Citations

Lyall KA, Hurst SM, Cooney J, Jensen D, Lo K, Hurst RD, Stevenson LM. Short-term blackcurrant extract consumption modulates exercise-induced oxidative stress and lipopolysaccharide-stimulated inflammatory responses. Am J Physiol Regul Integr Comp Physiol. 2009 Jul;297(1):R70-81.

www.doi.org/10.1152/ajpregu.90740.2008

Hurst RD, Lyall KA, Roberts JM, Perthaner A, Wells RW, Cooney JM, Jensen DJ, Burr NS, Hurst SM. Consumption of an anthocyanin-rich extract made from New Zealand blackcurrants prior to exercise may assist recovery from oxidative stress and maintains circulating neutrophil function: A pilot study. Front Nutr. 2019 May 29;6:73.

www.doi.org/10.3389/fnut.2019.00073

Hurst RD, Lyall KA, Wells RW, Sawyer GM, Lomiwes D, Ngametua N and Hurst SM. Daily Consumption of an anthocyanin-rich extract made from New Zealand blackcurrants for 5 weeks supports exercise recovery through the management of oxidative stress and inflammation: A randomized placebo controlled pilot study. Front. Nutr. 2020;7:16.

https://www.frontiersin.org/articles/10.3389/fnut.2020.00016/full

IMPROVES RECOVERY AFTER EXERCISE

The specific health effect proposed for New Zealand blackcurrant is the management of moderate exercise-induced oxidative stress and inflammation which leads to improved exercise recovery. A number of clinical trials have also demonstrated blackcurrant extract can reduce measures of muscle damage and fatigue like creatine kinase and lactate (Hutchison et al. 2016; Willems et al. 2015; Lyall et al. 2009).

Citations

www.doi.org/10.1152/ajpregu.90740.2008

Dannapfel S, Lowe T, Cummins R. The acute effect of prolonged intense cycling and blackcurrant extract on protein carbonyls in well-trained male cyclists. J Sci Med Sport 12S (2009) S1–S83.

www.doi.org/10.1016/j.jsams.2008.12.166

Hutchison AT, Flieller EB, Dillon KJ, Leverett BD. Black currant nectar reduces muscle damage and inflammation following a bout of high-intensity eccentric contractions. J Dietary Suppl. 13(1):1–15, 2016.

https://linkinghub.elsevier.com/retrieve/pii/S1440244008004039

www.doi.org/10.1080/1028415X.2018.1525950

Barnes M, Perry B, Hurst R, Lomiwes D. Effects of Blackcurrant extract on peripheral blood flow and muscular endurance. Med Sci Sports Ex 2018 May:50(5S):720

www.doi.org/10.1249/01.mss.0000538374.17437.0b

www.doi.org/10.3389/fnut.2019.00073

www.doi.org/10.3389/fnut.2020.00016

Manages Inflammation for Tissue Repair

A number of studies show blackcurrant extract speeds the body’s own inflammatory defences toward tissue repair. For example, it appropriately modulates the production of pro and anti-inflammatory or immunomodulatory cytokines like TNF-alpha, IL-6, and IL-10.

Citations

https://journals.physiology.org/doi/full/10.1152/ajpregu.90740.2008

Hutchison AT, Flieller EB, Dillon KJ, Leverett BD. Black currant nectar reduces muscle damage and inflammation following a bout of high-intensity eccentric contractions. Journal of Dietary Supplements. 13(1):1–15, 2016.

www.doi.org/10.3109/19390211.2014.952864

www.doi.org/10.3389/fnut.2019.00073

Hurst RD, Lyall KA, Wells RW, Sawyer GM, Lomiwes D, Ngametua N and Hurst SM Daily consumption of an anthocyanin-rich extract made from New Zealand blackcurrants for 5 weeks supports exercise recovery through the management of oxidative stress and inflammation: A randomized placebo controlled pilot study. Front. Nutr. 2020;7:16.

www.doi.org/10.3389/fnut.2020.00016

SUPPORT TRAINING ADAPTATION

New Zealand blackcurrants don’t act as antioxidants in human plasma (Hurst et al. 2019). The management of exercise oxidative stress and inflammation is unlikely to be attributable to the antioxidant properties of the extract and more likely due to blackcurrant activating adaptive defensive pathways in cells and tissues. This potentially occurs through blackcurrant anthocyanins working with exercise to modulate Nrf2-antioxidant response element signalling pathways. Additionally daily consumption of New Zealand blackcurrants over 5 weeks either maintained or enhanced exercise recovery effectiveness, improving anti-inflammatory and immunity measures (Hurst et al. 2020).

Citations

www.doi.org/10.1152/ajpregu.90740.2008

Dannapfel S, Lowe T, Cummins R. The acute effect of prolonged intense cycling and blackcurrant extract on protein carbonyls in well-trained male cyclists. J Sci Med Sport 12S (2009) S1–S83.

www.doi.org/10.1016/j.jsams.2008.12.166

Braakhuis AJ, Hopkins WG, Lowe TE. Effects of dietary antioxidants on training and performance in female runners. Eur J Sport Sci. 2014;14(2):160-8.

www.doi.org/10.1080/17461391.2013.785597

www.doi.org/10.3109/19390211.2014.952864

www.doi.org/10.3389/fnut.2019.00073

Hurst RD, Lyall KA, Wells RW, Sawyer GM, Lomiwes D, Ngametua N and Hurst SM Daily Consumption of an anthocyanin-rich extract made from New Zealand blackcurrants for 5 weeks supports exercise recovery through the management of oxidative stress and inflammation: A randomized placebo controlled pilot study. Front. Nutr. 2020;7:16.

www.doi.org/10.3389/fnut.2020.00016

A Unique Berry

New Zealand blackcurrants aren’t just any other berry. This powerful polyphenol superfood delivers enhanced performance and faster recovery thanks to a unique and one-of-a-kind combination of anthocyanins that can’t be found anywhere else in the world.

Blackcurrant Extract Supplement

There's nothing better than eating fresh berries, but they are not always in season or convenient to get. 2before's blackcurrant extract supplement delivers the benefits of natural food in a powder form that tastes great on its own, or blends with your usual pre-workout to make it more effective.

Adaptive Anthocyanins

New Zealand blackcurrants act as a pre-exercise primer to increase plasma oxidative capacity. This triggers your body’s antioxidant and inflammatory defense and recovery systems, so you’re ready to go as soon as your workout begins.

Delphinidins (Pro-oxidant)

Pro-oxidants in 2before switch on your body’s own antioxidant system, helping you to push harder for longer. Taking it 30-60 minutes before exercise helps you reach maximum saturation for optimum cellular priming.

Cyanidins (Anti-Oxidant)

On their own, antioxidants don’t help exercise or recovery —but our unique blackcurrant variety combines antioxidants with pro oxidants, unlocking your extra performance.